Taking mangosteen may increase the risk of bleeding in people with bleeding disorders. Taking mangosteen may increase the risk of bleeding during or after surgery. Stop taking mangosteen 2 weeks before surgery. Taking mangosteen together with medications that also slow blood clotting could increase the risk of bruising and bleeding.
Mangosteen is likely safe for most people, but it may increase the risk of bleeding. Consult your healthcare provider before taking a new supplement or drastically changing your diet.